Food Safety, Nutrition and Veterinary Public Health Department, Istituto Superiore di Sanità – Mantovani is a senior toxicologist of the Italian National Institute of Health (ISS), with a long-standing expertise on risk assessment, e.g. at EFSA. The interdisciplinary collaboration in risk assessment drove him toward One Health. Under this respect, his activities include “The Environment-Animal-Human Web: A “One Health” View of Toxicological Risk Analysis” (Frazzoli& Mantovani, eds.), Front Public Health 2018; and the international OHEJP Summer School (2021). “Environmental issues in One Health”.